Transplant: Varicella Zoster Table 1

Indication	Drug and Adult Dose	Drug and Pediatric Dose	Duration
Primary varicella	Acyclovir 10 mg/kg IV Q8h	Acyclovir 10 mg/kg IV q8h	Antivirals are to be given for at least 7 days or until lesions are custed. In SOT recipients treatment might need to be prolonged as crusting of lesions is usually delayed or for more invasive disease.
Localized Zoster	Acyclovir 800 mg PO 5 times a day Valacyclovir 1g PO TID Famciclovir 500 mg PO TID	Acyclovir 20 mg/kg PO 4 times a day Valacyclovir 20 mg/kg PO TID
Disseminated Zoster Organ invasive disease Zoster ophthalmicus Ramsey-Hunt Syndrome	Acyclovir 10 mg/kg IV Q8h	Acyclovir 10 mg/kg IV Q8h

Indication

Drug and Adult Dose

Drug and Pediatric Dose

Duration

Primary varicella

Acyclovir 10 mg/kg IV Q8h

Acyclovir 10 mg/kg IV q8h

Antivirals are to be given for at least 7 days or until lesions are custed.

In SOT recipients treatment might need to be prolonged as crusting of lesions is usually delayed or for more invasive disease.

Localized Zoster

Acyclovir 800 mg PO 5 times a day

Valacyclovir 1g PO TID

Famciclovir 500 mg PO TID

Acyclovir 20 mg/kg PO 4 times a day

Valacyclovir 20 mg/kg PO TID

Disseminated Zoster Organ invasive disease Zoster ophthalmicus Ramsey-Hunt Syndrome

Acyclovir 10 mg/kg IV Q8h